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histamine intolerance after menopause

Women's Health | Last Active: Dec 10 12:12am | Replies (61)

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@laberg1

Thanks for all the information. I have histamine intolerance, for the past 3 years. I break out in hives. Antihistamines do not help. Once I get into the state of huge hives the only thing that can get me out of it is prednisone.

I take B6 and Saccharomyces Boulardii (the only probiotic that I can tolerate) They are precursors to the DAO enzyme that breaks down histamine.

I also take: Vitamin C, quercetin, bromelain, stinging nettle and NAC. And Ashwagandha for sleeping. These seem to control it a bit.

But: If I eat or drink: wine, vinegar, lemon, orange, fermented foods and chocolate. Or foods containing cinnamon, nutmeg then the hives return.
Today, I was googling and found that a lack of progesterone and too much estrogen can be a cause of histamine intolerance . I am planning to get those numbers checked.
Hope this helps. And wishing you well!
Linda

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Replies to "Thanks for all the information. I have histamine intolerance, for the past 3 years. I break..."

I am sorry about your symptoms. Hives are terrible! I really went through a lot of research and so many specialists and your case makes me wonder if you may actually have chronic urticaria. It can be triggered by foods.

On the progesterone/estrogen imbalance thing: I did read about that last year and gave it a try. Progesterone is thought to up-regulate DAO. It worked spectacularly! For awhile 🙁 . The pills worked, but only if I took them in the morning because they only last in your system for a few hours. Also, they make you feel sick and dizzy and it's dangerous to drive. My advice to you is to use the creams: it is absorbed through the skin fairly efficiently and does get in to your system (I checked with blood work). It stays around for about 48 hours. I had to use A LOT to get any benefit. I don't know how healthy it is in the long-term. My guess is that it stopped working when I literally ran out of B6 to make DAO.

Best of luck.

Another thing about the progesterone: It is known to cause skin flare-ups and after taking it for awhile at such a high dose (I think I was rubbing in 150 mg a day) it did just that. So it added skin inflammation to my list of histamine intolerance symptoms: If I took a 1/4 teaspoon of olive oil (my histamine intolerance measuring device) within 1/2 hour I would have red patches and dermatographia all over my skin. So it could make the hives worse.