I for one can tell you that it works great for me. For 8 years I used the vaccum pump and bands. I found that system to be terribly uncomfortable and painful from the constriction. I was concerned about what affects I was having on my penis health because it would turn blue and cold in a short time. I finally gave up and just didn't have sex. I wasn't happy about that situation either so, after a couple of years of that I learned about Trimix and opted for trying it. It has changed my sexual experience tremendously. It isn't perfect because you have to experiment to find which amount works best for you. Since it's rather expensive you may want to experiment with what minimum dosage works best for you to have a successful sexual experience. Sticking a needle into the side of your penis is also something you will have to get used to. It hurts briefly but the syringe needles are quite small so it's more like a sting. I thought it worth the try and have used this method a number of times successfully. Good luck!