Low Dose Naltrexone has been a huge help in relieving the worst of my pain. I'd been using edibles mostly at night so I could sleep, but they are expensive. My pain was 6-9 24/7. I used pain cream during the day so I could function to some degree. But the LDN keeps my pain bearable. I still have to pace, as my pain increases if I don't stay in my energy envelope, but it has been a huge help in getting some relief. Pepcid and Zyrtec are what I'm on for the Mast Cell Issue. I still have gastrointestinal issues that she gave me a gastropathies diet to follow. And while my oxygen levels are fine, I'm short of breath often through out the day.