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When to check bone resorption/formation markers?
Osteoporosis & Bone Health | Last Active: Sep 25, 2023 | Replies (10)Comment receiving replies
Hi windyshores! I am uncertain about taking Evenity as my endo has recommended and have postponed the infusion until Oct. 4; since I have a history of a malignant sarcoma that occurred twice (1983 and 2004) cancer potential bone builders are excluded, but my endo sees Evenity as okay; I was looking for your comments on alternatives to Evenity, or maybe even a holistic approach instead. I have a notation for your July 19 comments about this but am having trouble finding it. Could you help me find it and/or suggest best alternatives for my case. My blood tests are all okay, I am 82, and have a T score of -3.8 for spinal verterbrae and pelvic bone. I have never had any bone building meds but am taking caltrate now.
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As far as I know, Evenity doesn't have the same concern for recurrence of sarcoma as Forteo and Tymlos. The black box warning for those drugs about causing bone sarcomas was lifted but the caution for those who have already had a sarcoma is still there. I don't see anything in the insert for Evenity on this: the warning is about heart attack, stroke, cardiovascular events (and the difference between Evenity and placebo looks small).
From the info online it looks safe. It is hard when our endos don't know cancer and our oncologists don't know bones, but you can ask them of course. I often find that pharmacists are good for these questions and even calling Amgen, the manufacturer.