It's been mentioned here maybe already but I recommend a Youtube video which shows a medical presentation earlier this year on the effects of taking different osteoporosis drugs on bone density. It showed that the order you take the drugs makes a big difference on the results. The video is called "Combined and Sequential Approaches to Osteoporosis Therapy" in which Dr. Leder summarizes the results of different drug studies. It is a presentation for doctors, and all drug names are the non-brand name (ie. Evenity is robosozumab). So look up all the drug names first and write them down to help follow along. I had to watch the video more than once. Dr. Leder's presentation showed that it is best to start with a drug like Evenity (de novo meaning the first osteoporosis drug you take) and then change to an antiresorptive like Fosmax, Reclast, Polia, etc. He also showed the decrease in bone density if Evenity is not followed with another medicine to lock in the gains. He mentioned that following Evenity with Prolia is fine to lock in gains, but if you stop Prolia your bone density plummets.