Hi @jj8431, Welcome to Connect. Sorry to hear you are having the extreme sweating side effects from prednisone. Connect is a great place to share and learn from each other on what works and helps with our treatments. For my 2 occurrences of PMR, I just took my days prednisone dose in the morning along with my blood pressure meds. I never needed to split my dose because it kept me pretty much pain free until the following morning when I would wake up with some stiffness and at times a little pain. My rheumatologist had me keep a daily log with my levels of pain and prednisone dose for the day which really helped when tapering. If my pain was higher than 2 to 3 on my scale, I wouldn't taper down to the next lower dose and would either stay at the current dose or increase by half of my previous taper depending on my level of pain. The one lesson I learned from my rheumatologist was we are all a little different with levels of pain and when tapering we need to listen to our bodies and taper accordingly.

I was started on 20 mg prednisone for both occurrences of PMR but I know others that have started on lower doses so I've often wondered if the starting dose may be the problem when the pain doesn't stay controlled during the night.

Has your rheumatologist offered any suggestions to help with the extreme sweating?