@darlingtondoll I am very sorry to hear that you are paralyzed AND deal with severe PN as well. My heart goes out to you as well as all of the sufferers of PN whose stories I have red about on this blog. Although my wife does not always have it 24/7 (sometimes it's less than the 24 but it's always the 7) the days she does get it all day is very debilitating for her. That is why the mitochondrial things have helped her so much. As I understand it from my online research, the MitoQ functions similar to CoQ10 in that when the mitochondria expel waste products (called ROS -reactive oxygen species) MitoQ helps to dispose of the waste which makes the mitochondria healthier. One of the problems with mitochondria, like anything, is that they can become sick and die and we have less of them as a result the older we get. All of the supplements I mentioned have a separate function in helping to keep mitochondria healthy and prolific.
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I am glad you at least have medical marijuana to rely on. My wife wants legalization in our state (Tennessee) asap! Marijuana has been so misunderstood and mischaracterized for so long it's pathetic. The dumbest thing many people have believed and continue to believe is that it is a gateway drug. I had plenty of experience in the 1970s using it myself to understand that it is NOT a gateway drug. Smoking marijuana does not make you want to use cocaine or heroin, etc. The fact that people still refuse to try to understand it even now is SUCH a disservice to people like you and my wife. Best wishes to you!