A possible clue... There is a connection between this vaccine (Shingrix) and aggravation of an Epstein-Barr infection. EBV is the cause of MONONUCLEOSIS. After a bad reaction to the vaccine, y monocyte levels were though the roof. The ER doc, my primary care docs, and a Rheumatologist at a well respected hospital failed to address this, as well as other extreme reactions. As a matter of fact , I have yet to get a referral to any docs with immunological smarts.