Batsam10, be very careful about postponing biopsies with a rising PSA. I've not heard of biopsies causing the problems your brother had. Sorry to heard about that.
In my case, I was tuned in to PC because my Dad had it. I'm 71 now, but when 70 my PSA had steadily risen over the past 5 years to over 5. I had the standard 12 core biopsi last year - revealed no cancer at all. When my PSA kept rising to 6, I was concerned - so I had a fusion biopsy - which means they did an MRI and combined that image with the ultrasound when they did the biopsy. I had 3 cores of Gleason 8 and 1 core of Gleason 7 (4+3). After considering my options, I chose Proton Radiation Therapy from UHFPTI in Jacksonville. Just prior to treatment, they did a PETSCAN and everybody was surprised and I was shocked to see that I had 7 lymph nodes with cancer. So my tidy little contained cancer was now Metastasized. And at treatment start, my PSA had risen to 11. Changed my treatment dramatically, but luckily I'm 67% through my treatments and Docs expect a great result.
The point I'm trying to make is that everybody considers Prostate Cancer to be slow growing and that we're all going to get it if we live long enough, and it's not that big of a deal. But the truth is it can be VERY aggressive and metastasize before you know it. I'm told the 12 core standard biopsy is like looking for a needle in a haystack. Having an MRI and fusion biopsy is better.
I chosen Proton Radiation Therapy because it's radiation stops at the tumor, whereas traditional Photon radiation radiates you all the way through the tumor and out of the body. Means less issues with side effects. Doesn't cost you anything to get a second opinion. ps. My Urologist never even mentioned Proton Therapy. You have to do your own research.
All my best to you - catch it early.
Tom