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Why is volume of the cancer not used?
Prostate Cancer | Last Active: Sep 22, 2023 | Replies (26)Comment receiving replies
Again you are saying aggressiveness, and that means 4. Which case has more 4? Doesn't matter if one is simple or not, which case has more aggressive tissue?
*Case 1 has a 3+4 lesion at 2.1 cc, the 4 at 49% and the 3 at 51%. So that means the part that composes 4 is about 1 cc total. Total count of 4 = 1 cc.
*Case 2 has a 4+4 lesion but only about 0.2 cc. Total count of 4 = 0.2 cc
Looks to me like Case 1 has way way way more aggressiveness in it.
Replies to "Again you are saying aggressiveness, and that means 4. Which case has more 4? Doesn't matter..."
4 mutant radically
A petrie dish with 0.2cc 4+4 Gleason can grow at a much higher doubling time
Than larger amount of 1.0cc 3+4
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You can not know at what time frame the grade 4 started .. you would need time study of several biopsies, without treatment. these studies have most likely been recreated in the labs with micros, and this is the science they base protocol on..these protocols most likely get reevaluated with every new proven theory..this being why the major clinics have the latest and usually best available treatments