Below are excerpts from a 2017 publication on MBST, This was before Tymlos and Evenity but I doubt much has changed. I found them very interesting. (Hopefully the link copied properly)
Nuclear magnetic resonance therapy (MBST) in the treatment of osteoporosis. Case report study - PMC (nih.gov)
Introduction
Despite various pharmacological treatments the problem of osteoporosis is not yet solved nor decreased (1–3). About the application of bone modifying drugs existing real life data do not support clear relevant anti-fracture effects (4, 5). On the contrary, new problems appeared such as drug’s adverse event and fractures after long term of pharmacotherapy. Additionally, there is still an absence f any early prevention and a lack of education about the bone and skeleton in general.
A big problem related to osteoporosis is also the fact that there is no diagnostic method able to measure the bone strength, on which depends fracture risk. BMD, usually used in clinical practice as a diagnostic “golden standard”, is not reliable for assessing the risk of fractures, especially for assessing therapeutic effect. The best evidence of a successful treatment is the resistance of the bone on the strong force which happens in severe trauma, but it is not possible to make a double blind, prospective, placebo controlled clinical study based on purposely exposing patients to accidents with potential fracture trauma. However, well documented case reports could be important evidence despite the fact those aren’t prospective double-blind, randomised studies
Good info. Thanks