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Very High PSA: What might cause a sudden increase?

Prostate Cancer | Last Active: Aug 9, 2023 | Replies (18)

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@rice

December of 2021 biopsy showed I had a 3+4 cancer in one core I sent the biopsy to John Hopkins they down graded it to 3+3. I started watchful waiting. Blood test every 90 days average around 5 PSA. In January 2023 I had a second biopsy no new findings. in June I had a MRI and a PET Scan nothing new. In July my blood test was 50.4. I tested 2 days later it went down to 43. I am having another test Tuesday . Any Idea what could be causing such a rapid raise in PSA ? I have no symptoms of an infection, but the doc gave me a antibiotic anyway.

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Replies to "December of 2021 biopsy showed I had a 3+4 cancer in one core I sent the..."

The PSA is very high. A 3+3 would be low risk though. The only caution here is that biopsies are those taken and not all of prostrate. It is why when you get radiation treatments they treat the entire prostrate as the biopsies might miss an area.

When you said every 90 days your PSA is around 5. A 5 is above normal but below 4 is normal. But the blood test you listed in your post said it was 50.4. That is quite a difference? Is this number the PSA test results also?

Do you bike ride? Are they doing a Free PSA or just PSA?