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How accurate are the PSA Tests?

Prostate Cancer | Last Active: Sep 27, 2023 | Replies (35)

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@rockin2047

The takeaway I get from the following websites is that zero PSA does not even exist. Read about The definition of a "ZERO" PSA is discussed here: 1st go to https://www.healingwell.com/community/ 2nd enter ZERO PSA into the search field in the upper right corner and click Enter button 3rd click on discussion of What's the Definition of "Zero" or "Undetectable PSA" ?
Also read Changes in PSA During Advanced Prostate Cancer https://www.webmd.com/prostate-cancer/prostate-cancer-psa-levels In one paragraph it says "Your prostate makes PSA. So do most prostate cancer cells." Say whaaat? I thought PSA only came from healthy prostate cells. Geez, I feel like I'm in my first year of med school!

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Replies to "The takeaway I get from the following websites is that zero PSA does not even exist...."

Thanks for sharing. I am just as confused. At one time, 0 PSA is defined as < 0.1. Because that is the level that the lab test can go. And also because it was believed that can only be achieved surgery. That is defined as 0 PSA. It is a cure. The others cannot. It is only under control. Then radio and hormone treatments can also get to that level. So their lab test developed 0.0 and even 0.00. The idea was only surgery can get that. The best radio and hormone can do is 0.0. But that seems to be also possible. So the old saying that only surgery can cure becomes open. Indeed, what is a cure? 0.1? 0.01? 0.001? Even surgery cannot always get to 0.001.
If you are in medical profession or school, may be you can offer some insight?