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@cpttommy

Thank you for your very interesting reply. Let’s specifically what I’m looking for is treatment based on what fax there are from the national Institute of health NIH.
I want to start from the root fact of what factually Root Mane is approved for by NIH.

My intuitive training tells me that I do want to spend my time trying to find a fix for the problem first.

I don’t want to waste time on commercial ventures that are based on speculation. Most opinions are just that -opinions!

What would be very interesting is to find a mayo clinic specialized individual or team where is acting upon fax or recommendation from the NIH.

I hope I have at least attempted to clarify a logical search sequence. The American public deserves the service based on my direct contributions to the United States of America over 55 years.

Any help of your expertise is much much sincerely appreciated.

Regards, Tommy Schmitt CptTommy

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Replies to "Thank you for your very interesting reply. Let’s specifically what I’m looking for is treatment based..."

Here are a few research articles on Lion's Mane.

---Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720269/
--- Therapeutic Potential of Hericium erinaceus for Depressive Disorder: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982118/
--- Four Weeks of Hericium erinaceus Supplementation Does Not Impact Markers of Metabolic Flexibility or Cognition: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762243/

Hi Tommy, The National Institutes of Health is an umbrella organization with many functions.

One of those is is the National Center for Complementary and Integrative Health, and one small piece of their mission is to gather and vet information about supplements. (https://www.nccih.nih.gov/health/herbsataglance) At this time, they do not have an entry for Lions Mane mushrooms

Another, and truly the most useful from a research point of view, is the National Library of Medicine, which provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. However, most articles are scholarly publications with published credentials and citations to support the abstract. This is the information @johnbishop cited for you.

The largest function of the NIH is to support scientific and medical research with grants to universities, hospitals, non-profits and even corporations. From their home page "the agency has grown to be the world’s largest source of medical research funding and the driving force behind decades of advances that have expanded fundamental scientific knowledge and improved health."

These may be applied for and granted through any of the many "arms" of NIH, which you can see listed here: "https://www.nih.gov/institutes-nih/list-institutes-centers"

So, the best we can offer you is our research results, which John shared above. Interest in herbal medicines and supplements has exploded in the past decade - at a far faster pace than anyone can design, fund and conduct clinical studies on all of them. It seems the medical profession concentrates on those which pose the greatest potential benefit or risk to the most people. I guess Lions Mane has not made the "hit parade" yet, except for these papers we cited.
Sue