That's "only" about a 30% increase in one month. The numbers are huge by comparison to mine and suggest an aggressive cancer that needs to be treated soon, so I don't mean to make light of it by any stretch.

My numbers, although much lower in absolute terms, basically doubled (100% increase) every month before starting treatment, and increased once more after treatment began, before starting their downward trend. The percentage change is one factor to consider as part of the overall assessment.

Different people have different biology and chemistry... some don't produce CA19-9 at all, some produce more than others in a similar state, and anyone's CA19-9 can have multiple contributors to their abnormally high level.

I just hope his doctors don't waste too much time evaluating his progress on Folfirinox. If his response is unimpressive or mixed with bad side effects, it might be worth trying a different regimen sooner rather than later. I think 6 months on Folfirinox was kind of a waste on me, when the response trend was already pretty evident by the 3rd month. The fact that I'm getting a better response to GAC makes me wonder where I'd be if we had switched to that before my Whipple.

Anyway, @mommacandy , you continue to be a hero/heroine. Many blessings and best wishes to you!