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Sophie93 avatar

How bad is a spine T-score of -4 ?

Osteoporosis & Bone Health | Last Active: Jun 21 8:01pm | Replies (90)

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Sophie, both Forteo and Tymlos slow progression. They have the advantage of increasing bone mass more powerfully than the bisphosphonates. Current thinking is to take the bone building drugs first because bisphosphonates (Fosamax) blunt the effect of the anabolic drugs (Forteo, Tymlos). There is some buzz about combination therapy.
You might contact your physicians' offices and ask them to consider anabolic drugs. I would specify Forteo (windyshores might say Tymlos).
If you don't have your bone marker results, you might ask for them.
Our bones break down so that they can be rebuilt to protect against fracture according to our current activity. The new spicula (the slender bones called trabecular bone) in the center of the bone realigns itself (anisotrophy) so as to provide the greatest strength for the angle of impact. If you are jumping out of airplanes, or skipping rope it prepares the bone for that particular angle. The bisphosphonate stop that process by preserving old bone.
It may be that Fosamax is the best drug for you right now. You might want to see an endocrinologist who specializes in osteoporosis. But be assured that those powerful drugs are waiting for you whenever you need them.

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Replies to "Sophie, both Forteo and Tymlos slow progression. They have the advantage of increasing bone mass more..."

Thank you for your elaborate&helpful reply! I understand... Luckily I have an upcoming appointment with my endocrinologist the coming week. I will mention Forteo and see how he reacts... In the meantime, I'm keeping up with my exercise routine (walking every day religiously), eating healthy and minimizing smoking (this one is the hardest for me, I have to admit). I was thinking about supplements, but not sure if I should even start them at this point.

@gently
Hi I have been managing BC for 1bouot 14 yrs. It was discovered to be metastatic to a vertabrae in late '23. It has been in "sleeping" mode I was told in the last yr. NO increase since the Met. diag. I take half dose of Anastrozole and have had dental surgeries to molars so have only has 2 Zomeda infusions a while back now & my diag. of Osteopenia just last mo. after a Dexa is now showing upwards of 3 to the lower spine and hips. I have another dental sugery pending...and took a NIA dance class last wk & was trying to take it easy, but have a lot of moving of boxes, and house wk from 2 pets...and next thing you know it seems like a sm fracture to a rib from 10 yrs ago flared up w/ I think "The Body keeping score" of all I did in the last 3 wks...So the thing about our bones if we do the right exercises rebuilding I am gather that what you mean by that is unfractured bone rebuilding. I am so nervous abt. this avg. pain in that rib that has been lessening since I have been trying to take it easy & do not think I will do that dance class this wk...What does anyone suggest about how to "rebuild" through exercise? a sm rib fracture that wasn't bothering me until I did this dance movement class called NIA. ? Additionally, I have a tendency for some buldging lower back disc issues if I do bending over doing to much lifting & bending over type things like yard wk .