I just completed cycle 6. Doing OK. Increased chemo brain this round which had me down for a few days. Since we last communicated my oncologist has suggested a revised protocol. Moving from 8 cycles to 12 cycles if I can tolerate it. Not thrilled about the idea but there’s data indicating better efficacy with increased cycles. I’m going to try and get through it. Neuropathy is one of the most common side effects of one of the chemo drugs in the combo. Oxaliplatin. For most patients the neuropathy is temporary but in about 25% of patients it can be permanent. My doc would like me to continue as long as possible but if the neuropathy becomes debilitating he will stop. Fortunately this cycle the neuropathy has not been bad so far. I’ve been doing Accupuncture which I believe helps. Overall I haven’t had many of the side effects that they warn of. My gut has held up pretty well and I eat a fairly normal diet. I haven’t lost any weight so far. Everyone will have different experiences and even from one cycle to another I’ve had various experiences. It’s a long journey and it can be very discouraging. Support from family and friends is so important to try and stay positive. On the days that you feel better be sure to get out and enjoy the fresh air. Best of luck to your husband and let me know if you have any questions or feedback as he goes along.