@madeleine40 , I took Fosamax followed by 5 years of Reclast during 2000-2010. Dexa stayed stable with osteopenia until 2021 when it changed drastically to severe osteoporosis. Fearing fractures I followed by rheumatologist recommendation for Prolia. At that time I had not done any research into osteoporosis treatments. Anyway, in the 2 years I was on Prolia, I had 3 unusual pathologic fractures. So, 2 months ago I started on Tymlos as my only option now. My rheumatologist said that I will need to go back to Prolia as I have exhausted the amount of time for taking Reclast. However, he is not an osteoporosis specialist so I’m currently looking for someone.