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How long can I stay on Prolia?

Osteoporosis & Bone Health | Last Active: Sep 5, 2023 | Replies (10)

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@tetris

I saw from another thread that you found Keith McCormick's excellent Aug 2022 OsteoBoston interview. You might also find his Feb2023 interview with Margie Bissinger re: osteoporosis medications helpful (https://margiebissinger.com/186-osteoporosis-medications-pros-and-cons-dr-r-keith-mccormick/). They discuss Prolia starting around 34:30 (minute:second). I recommend listening to the entire episode if you have time.

Personally, I find Prolia a scary medication, especially with its potential for a rebound effect if it is not prescribed or taken properly. I currently take Forteo (an anabolic medication, or bone builder) and will follow it later with Reclast, a bisphosphonate (which Fosamax is too, though Reclast is taken intravenously and Fosamax orally). It is my understanding the sequence of an anabolic (e.g., Forteo) followed by a bisphosphonate (e.g., Fosamax) is more effective than a bisphosphonate followed by an anabolic. I do not know if that changes depending how long ago you took a bisphosphonate before an anabolic.

I think you will find Dr. McCormick's "Great Bones" super helpful re: Prolia, e.g., starting at page 545 (it's a reference book, not leisure reading!) along with the resources teb and others have mentioned in various threads. If you have the financial resources, you may find a consult with Dr. McCormick very helpful too.

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Replies to "I saw from another thread that you found Keith McCormick's excellent Aug 2022 OsteoBoston interview. You..."

Thank you so much for your reply and links. I looked up Dr. McCormick’s website and reviewed all the material he needs for an initial consultation. I’ll have to my clinic to see if those test were even done. I think the money is worth spending as my long term health and activity is well worth the $300 or so! I really appreciate all the advice and comments from this forum. Extremely helpful.