I’m here and traveled alone. Come a day early and find the the best way to get from your hotel to the Mayo Clinic. Then give your self time to get lost (I came on a Sunday and everything was closed) I would recommend getting to the Clinic on the street level. The “Skyways” are way too confusing. Then getting around the hospital either for testing or bloodwork go down to the “subway” which is just underground walkways. There are many “Help” desks all over. Everyone has been wonderful and very helpful. Hope this helps