Hi @lanewright, I wanted to check in first to see how you are doing. Hopefully your doctor has found a treatment that is working for you. My husband lost his leg to LMS in March 2023, we found it had spread to both lungs and had 1 of 3 nodules removed in June. We went back for a follow up scan last week (August) and found that he now has multiple new nodules and they are growing. With surgery no longer an option he is set to start chemo next week, they plan to do 2 rounds then another CT to see if it is working before continuing. Like you, we were given little hope and have found it extremely hard to find any information online about LMS treatments, survival or what to expect. We are hoping to visit Mayo for a second opinion, mainly to confirm that the path we are on is the correct one. Hope you are doing well and we are sending prayers your way.