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@billfarm

No detectable distant masses last pet scan bloodwork described as perfect. 6 of 35lymph nodes removed with prostrate positive. Summary of last med oncologist described me as stage 4a. ADT managing psa @ 0.0 for 6months now.Having trouble rationalizing radiation and recovery from accompanying side effects if I will require adt life long anyway to control metastisised pc cells.

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Replies to "No detectable distant masses last pet scan bloodwork described as perfect. 6 of 35lymph nodes removed..."

No distant metastases on your scan may not mean there are not distant metastases, just too small to be seen.
It may mean exactly that, none.
Who said ADT for life...? Many of the newer treatment paradigms such as doublet or triplet therapy are for defined periods, 18-24 months, if the response is positive, treatment is stopped and you go on active monitoring, typically every three months with defined criteria for going back on treatment. Here's an example - https://www.urotoday.com/video-lectures/asco-2023/video/mediaitem/3500-a-phase-2-trial-of-adt-interruption-in-patients-responding-exceptionally-to-ar-pathway-inhibitor-in-mhspc-a-dream-atish-d-choudhury.html?utm_source=newsletter_11982&utm_medium=email&utm_campaign=prostate-cancer-daily

In my case, that off treatment was 4-1/2 years.

I'm on treatment now, six to twelve months, given my response, we'll stop and actively monitor.

How long off treatment this time, time will tell.

Lifetime of ADT, nope.