I also have multiple issues going on. I was diagnosed with inflammatory arthritis, with some joints having osteoarthritis and some rheumatoid arthritis, as well as range of immunologic/nflammatory issues - lichen sclerosis, rosacea, eczema, blepharitis, swollen fingers, to name a few, plus type 2 diabetes. I am also positive for MGUS. M

Last fall I had the worst flare of pain so made an appointment with a rheumatologist, bypassing my PCP. My pain was primarily in my hands and worsened by cold. I also was RFneg, but had had a very high CRP (I believe it was only recently that RFneg disease was recognized as a thing.) That's when I learned about MGUS. My first rheumatologist started me on Plaquenil, but I have had some breakthrough pain. Last month I started with a new rheumatologist after the first one went on to a new position. He added methotrexate, with prednisone to help until the methotrexate started.