Hi Helena, I started being treated with gemzar & abraxane in June, every 2 weeks & now every 3 weeks because my bloodwork usually came back low. My first chemo was in October 2022 with Leucovorin, Fluorouracil, Oxaliplatin & Irinotecan, which I had 12 or 14 courses. I'm only on my 5th or 6th treatment of g-a. I haven't had many side effects especially if I remember to keep drinking! I had one episode with side effects: achy joints, muscles, low grade fever up to 101 & physically wiped out. I found Tyenol helped relieve & reduce the side effects. I feel so fortunate I rarely have had nausea or diarrhea but I suffer with constipation a lot, so fiber is my friend! Another side effect is feeling tired out or lack of strength & stamina. Some days are better than others but I'm learning to take a nap when I feel so tired. Since I've been on g-a my cancer marker numbers have been going up. After my last CT, the tumor in the tail has only grown 4mm & the lesions on my liver have stayed almost the same. It is interesting how differently the chemo affects everyone, but that's what makes us all unique. I'm getting chemo tommorrow, so I keep hoping the drugs will affect my cancer. Take care.