Wow! Every 2-3 hours and a full time job! That is a lot! I nebulize first thing in the morning, usually 7am, and then about 5pm*, before dinner. I do wash equipment in soap and water after each time, rinse with hot sterile water and put on clean towel to dry. I soak in vinegar and water at recommended ratios every couple weeks and try to sterilize by boiling once a week (which my doctor recommends). I am often grateful that I'm not trying to work, raise kids and all that. I do take it when away from home and do the best I can, but often once a day is what happens. Same with when we have guests here. I am not nearly as strict as many people, nor as sick. I'm hoping to avoid the antibiotics, as well as further deterioration of my lungs, so the effort is worth it to me, but I don't stress when I don't manage to do the max. *Often that 5pm airway clearance is a little rushed and not quite as thorough, but better than nothing.