Yes @brighterdays, my Oncologist also said that women who have had breast cancer and have been on on Zometa have a higher 10 year survival rate. I will have my second infusion in October and I am making sure to drink a lot of water the day of the infusion and I will be telling myself over and over during the infusion that Zometa will help me and it will not harm me. I had 3 spinal compression fractures last fall right about the same time as my bc diagnosis and they are the pits. A good PT does help tremendously but it's just something you continue to deal with. Sending love and healing wishes to all ❤️