Decipher 0.61 Interpretation: Will this change treatment?

I had Decipher test done my Mayo Jacksonville. From my biopsies I was in the intermediate group. When I had the Decipher test it came back low risk. This changed my treatment recommendations from receiving hormone treatments to not recommending them based on results of Decipher.

This is for radiation treatments though. Is your husband having surgery? Is the cancer still inside prostrate? Has he had a bone scan, a Pet Scan? All these test help the oncologist set up treatments. I had 30 proton pencil beam treatments at UFPT. Mayo Jacksonville did not have proton radiation treatment to offer me.

Congrats on your downgrade. My husband chose surgery partly because he would need 18-24 months hormones with radiation. I don't think his downgrade would affect that because, although his biopsy was also downgraded by JHU, he still is Gleason 8 with two 4+4 cores. He has had a PET PSMA - clear. We checked into proton treatments in San Diego and Mayo Phoenix but they would require ADT (dealbreaker for him).

The surgery option was not presented to me because of my age and that I have heart failure. I really don't have much information on surgery nor hormone treatments. I presume ADT means hormones.

I have read a lot of troubling posts on taking hormones. From what I have been told by the oncologist it does not kill the cancer just stops the growth. Seems prostrate cancer feeds on testosterone to grow. So what every treatments you get are enhanced.

My worst Gleason was 7. 3+4. Good news on your husband's PET scan. Did he have the bone scan also? Both are good diagnosis for spread of cancer outside of prostrate. Catching it while still confined to prostrate is the stage you want to catch it at and treat for best outcomes.

The protocol is now the PSMA PET scan, which includes a CT. From what I understand, the bone scan is an older scan, considered not as accurate and I'm not sure if it's still used at major cancer centers.

CORRECTION - Decipher score was .61

I had the Prolaris and the Decipher test. Both are guidelines. Both were a little bit different in terms of the level of genomic risk which were relatively low but the doctors do consider them as an additional tool. I also believe doctors are a bit loose with the use of hormone therapy. I had 5 RO opinions with one suggesting ADT and the others not. My brother started it in January and is desperately trying to get off of it.