Hi meghan13. I can totally sympathize with what you're going through. I've been diagnosed off and on with pseudomonas for 4 1/2 years. I believe it is in a chronic stage now. I also have MAC and Bronchiectasis. I have also inhaled Tobramycin off and on during that period. Early this year I was really struggling with heavy coughing, fatigue and inability to gain any weight. I contacted my doctor by portal message but he was out on paternity leave. The doctor covering for him actually called me and said to stop the Toby and called in a 10 day Rx for Cipro 750 mg 3 times a day. The next day I had red circular place come up on my left calf and red spots on my right shin bone. My dermatologist saw me that same day and said it is an allergic reaction to the Cipro. I contacted the pulmonary doctor and she said she would back the dosage to 500 mg but could not go lower as I would not be getting any benefit. I got the 500 mg and finished the 10 days that way. I did not have any further reaction. Within 5-6 days my cough was much better and I felt well enough to start exercising. After that things got better and better. Coughing subsided and a cough became a rare thing. I don't know what reaction you had with Cipro but just wanted you to know my experience. I, being the skeptic I am, felt the pseudo would come back. It has been six months and I continue to feel fine. I do regular nebulizing the Sodium Chloride twice a day but that is just me making sure things don't go in the wrong direction due to me being "lazy." I don't ever want that awful feeling to return. Best to you. Faye