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48 years old with stage 1 ILC - Tamoxifen Advice

Breast Cancer | Last Active: Oct 1, 2023 | Replies (16)
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@leculdesac

https://www.nature.com/articles/s41416-020-01161-4#Sec11
I think it's this article. Maybe this one too: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931789/.

These, and a recent article series in Nature, introduced me to the newer "parallel model" of micrometastasis once cancer has become invasive. The idea is that the cells are already dormant, so what do you do to keep them that way--and what is no longer necessary. Fascinating debates.

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Replies to "https://www.nature.com/articles/s41416-020-01161-4#Sec11 I think it's this article. Maybe this one too: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931789/. These, and a recent article..."
Chris, Volunteer Mentor | @auntieoakley | Aug 22, 2023

I agree that it is all fascinating and there is much research being done everywhere on how to predict who will become metastatic and when. I read both of those, thank you for sending them, I was pretty shocked by the kind of blanket statement that 9 to 12 months was enough. Especially since I took 15 years of endocrine therapy. After reading them both I realized that it probably was your specific type of cancer that was essentially 9 to 12 months if the hypothesis is correct.
I think even knowing all they know now, I still would probably have had to do most of that. Lol 😂
I was really happy to read all of this because it means that newer patients go through less treatment, and less harsh treatments like chemo too. I have also been reading on how they are starting to pull back on radiation. Just mind boggling. 🤪
Are you still thinking 20% dose for starters, what does your doctor think?

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