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Rising PSA years after radical prostatectomy

Prostate Cancer | Last Active: Mar 5 7:14am | Replies (206)
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@richardblackman

At 71, 2 and 1/2 years after my Radical Prostatectomy . No issues, until now PSA has been < .006.
Test last week 6 months after the last .006, showed a PSA .117 . Not thinking, I did ejaculate either the morning of or day before the test as well as an hour bike ride the day before. Don't know if that has impacts once prostate is removed. Would it be time for imaging tests already or wait and see the next test results in 3 or 6 months. Will be seeing urologist this week, but wondering what I might be asking or what to expect. thanks

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Replies to "At 71, 2 and 1/2 years after my Radical Prostatectomy . No issues, until now PSA..."
michaelcharles | @michaelcharles | Aug 22, 2023

PSMA PET scans have greater accuracy at higher PSA levels.
I think below .2 sensitivity is 20 - 30 %
That said, it is thought that recurrence is from PCa cells in the pelvic area and/or pelvic lymph nodes.
I had IMRT radiation and 4 mos of ADT due to PSA .19 post prostatectomy.
Obviously, you need to consult with a Urologist and/or a Radiation Oncologist/Medical Oncologist.
Rising PSA is trended over 2, 3 or 4 tests, so first step probably is repeat PSA.
If rising, perhaps PSMA PET scan to rule out discernable distant metastases.
And then radiation and ADT.
But I am getting way ahead.
Prostate Cancer Foundation webinar on PSMA PET scan sensitivity an utilization at:
pcf.org
Upper right menu
Patient Resources
Click on arrow on right
Patient Webinars
March 14 2023
Good luck. Hope it's an anomaly and next test is back in line.

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gkm | @gkm | Aug 22, 2023

Ejaculation and bike riding will increase one's PSA reading. It is recommended that you avoid both prior to your PSA test. Google and you will find out how many days before to avoid those two activities. Make sure the PSA test is done at the same lab. I would not consider any imaging test yet but would recommend that you have another PSA test, either in 3 months or currently if that will give you peace of mind.

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