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@spino

When I look back at myself during that decision-making process, I see someone who wanted to minimize the severity of my situation. Fortunately for me, I got excellent prognostic information from the (second) mpMRI and mpMRI guided transperineal biopsy, in a city far away by a highly qualified practitioner followed by frank advice about my situation and a good referral. That is not always the case.
So my only addition to this discussion is to look as honestly as possible at yourself and listen closely to advice that goes against what you would like to hear. After all, ultimately you want to do what is actually best for your actual situation, not what is theoretically best for what you imagine your situation to be.
Of course, you may be better at telling yourself the truth than I am :-).

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Thank you so much for your reply. Lots to consider. Matt