I’ve been living with BFS for close to three years. Not terribly debilitating, but within the past few months, I’ve began getting more cramps in my calf area and tightness and pain in my feet. I’ve recently been suffering from recurring rashes and hives. It could be due to seasonal allergies, but I’ve looked into MCAS as a possible cause of my skin condition. Im No wondering if a histamine intolerance isn’t the underlying cause of my BFS. Of course stress can increase histamine levels and I have been a very high stress person (undermethylator) my whole life. I’m now looking into hormone replacement therapy (testosterone) as a means to calm down my histamine. I’ve researched that testosterone can help those with MCAS or similar conditions. I’m curious to see if it will help with the fasciculations. My neurologist just prescribed me Cymbalta and it made me feel anxious. I stopped using it after only a week.