I was offered Prolia, but chose Boniva. I was told that the advantage to Boniva is that it keeps working even after you stop taking it, so there’s a greater likelihood that you can take lengthy breaks. I also like the fact that Boniva is monthly. The advantage of Prolia is that it’s injectable, and you can consume coffee and/or breakfast right away. The disadvantages to Prolia are that you must go into the office for injections, and it’s expected that you’ll continue taking it for life. If Boniva interferes with your digestion, Prolia is a better choice.