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New, overwhelmed: What's microsatellite stable?

Pancreatic Cancer | Last Active: Aug 27, 2023 | Replies (17)

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@granite

I wish I had seen Dr Matthew Katz’s video 17 months ago. I may have presented it to our oncologist at top cancer center to go on the table immediately after diagnosis (with somatic mutation after presenting with high bilirubin levels.)
He quickly developed pancreatitis so the stent was needed, but it delayed treatment when it became obstructed twice and he had to be hospitalized. These delays may have contributed to the ineffectiveness of the neoadjuvant Folfirinox. What has Katz been presenting lately?

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Just one additional note to this; each case is so different vis a vis stage at diagnosis, where the tumor(s) are located, etc.
the cancer is often silent for a long time and is systemic in nature so if one is staged beyond 2 the likelihood is that there are cells hiding somewhere. Initial systemic therapy to attack those and shrink tumor makes sense to try. Surgery can be curative but “wack a mole” is not a game for the faint of heart and may prove to fail ultimately without adjuvant therapy/radiation. My initial pancreatic tumor is gone-it was necrotic when removed. My metastasis in liver were necrotic too-except one small spot. Liver margins were clear. Yet-I have a small reoccurrence. As much as I would like to just cut it out-I know I need to play the long game and try to clear my system.