I wrote a more detailed reply But it disappeared?? I did do much much research before we tried lions mane . It all looked safe , so we tried it . Gerri did not have diarrhea just very frequent bowel movements . We prayed for help and answers to the problem! I started going over all changes in food or anything that we did differently ! Gerri has also been on the same meds for years.I was getting mad that GOD was not helping us !! THEN .... I remembered the word that kept coming into my mind ...mushrooms!! I apologized to GOD and we quit the lions mane supplement.... problem GONE ! BTW the lions mane did nothing for her dementia problems