I started taking Creon about a month after my surgery (delayed as no one told me I needed it). My primary Dr. who by chance had the exact same procedure himself, prescribed it to me. Started at 2 1200 with each meal, but I had a hard time remembering to take it before eating. Got really good with breakfast, but because lunch and dinner were never the same time or even at home it was a challange remembering to take it. Once I finally trained my brain to take it regularly things got great. I also realized I only needed 1 pill with each meal. 3 1/2 years later it has spread to my liver and the stomach issues started coming back as well as yet another increase in blood sugar, seems it might be after what little pancreas I have left, but anyhow I am back taking 2 1200 pills with meals and things are almost back to normal. I will occasionally take a Gas-X after eating, which is almost immediate relief. Hopefully the Lanreotide injections will help control the spread of my cancer (2 shots in) and minimize any additional stomach issues. Fatty foods seem to be my biggest problem foods, but everyone's body is different for triggers.