I also experienced some minor Peripheral Neuropathy at about the same 6-month time frame at 6mg Prednisone. I felt numbness in my feet and the ends of my fingers. My neurologist suggested that I take Alpha Lipoic Acid and my rheumatologist recommended to take Vitamin B -- so the previous comment about high levels of B6 surprised me. I have been off Prednisone for 8 months and it is getting better.