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Help with PSA reading

Prostate Cancer | Last Active: Aug 19, 2023 | Replies (30)

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@pablo81

I believe under 4 is considered ok. .9 is pretty low. I am 81 and have a PSA of about 5.3.... Anything less than 10 at my age is normal............

It spiked to over 4 about 2 years ago.

I now take a PSA total + free test that measures total PSA and free PSA. This gives an estimate based upon medical model of whether and if you "may" have aggressive PC. It is an educated guess.

In my case I am just monitoring.

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Replies to "I believe under 4 is considered ok. .9 is pretty low. I am 81 and have..."

OK. I'm am also currently 81 yr. Perhaps this is a teaching moment.

Let's look at my data from the recent 17 yrs and see if might help you assess your prostate health. [The prior 16 years, my PSA was < 1.0].

Date PSA, ng/mL Increase, ng/yr** % Free PSA***
5/07 1.2 -
3/09 1.6 0.2*
11/11 1.8 0.1
2/14 2.6 0.3
1/15 2.3 - 0.3
6/16 2.9 0.15*
6/17 2.8 - 0.1 25
10/18 3.9 0.5 * 18
9/19 4.1 0.2 20
11/20 4.9 0.8 20
11/21 6.9 2.0 16
* Averaged over previous two years

** < 0.5 ng/mL/yr is a potential guideline

PSA Total Reference Range:
40 - 49 year old: 0.0-2.5 ng/mL
50 - 59 year old: 0.0-3.5 ng/mL
60 - 69 year old: 0.0-4.5 ng/mL
70 - 79 year old: 0.0-6.5 ng/mL

*** PSA,% Free
Probability of Prostate Cancer for Men with Non-Suspicious
DRE Results and PSA between 4 and 10 ng/mL

Percent Probability
Free PSA of Cancer
0-10% 56%
10-15% 28%
15-20% 20%
20-25% 16%
>25% 8%

So here are total PSA tracking data, velocity, total PSA as a function of age, and % free data. This is the data I and my primary care physician had to interpret. Do you see parallels with your data?

How would you interpret this data? Which, if any, of this data would raise your eyebrow or prompt you to see a urologist? If so, when?

Others should feel welcome to chime in.

I have further data since 11/21 which I will share after you and others have had an opportunity to make an assessment of the data above.