For the last 2 years I have been in the Janesen clinical trial proteus PCR 3011.. you can goggle this to see the long list of exclusionary conditions and I suppose that this is the situation to exclude men who have medical conditions ( other than a level of PC) that would effect the statical result. Hence, it is much easier to be excluded than included and it is not always good to participate as a large percentage of the men are given a pracebo and not the experimental drug treatment.