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"Tight" feet and laser therapy
Pancreatic Cancer | Last Active: Aug 12, 2023 | Replies (15)Comment receiving replies
I had worsening of neuropathy after oxaliplatin was stopped due to an allergic reaction. I was having mid symptoms. I stopped May 2, 2023. I believe that the neuropathy has finally stabilized. I am not having pain but my ability to use my fingers is reduced and my balance has been affected. Probably the dose could have been reduced but I was not that bothered by the symptoms. I knew that people with BRCA mutations specifically tend to respond to platinum drugs so I wanted to take the full dose.
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"I had worsening of neuropathy after oxaliplatin was stopped due to an allergic reaction."
That is a commonly known reaction. My neurologist (and literature) refer to it as "coasting."
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I found a summary of the POLAR study on icing and compression to treat Chemotherapy-Induced Peripheral Neuropathy here:
https://www.breastcancer.org/research-news/hand-cooling-compression-nearly-halve-risk-of-neuropathy-from-chemotherapy
It was specific to breast cancer patients on taxane meds (Taxol, Abraxane), but found benefit in both icing and (independently) compression.
As I thought more about the advice from @frygirl777 's oncologist about NOT icing with oxaliplatin, the more it made sense.
If you were in a dark room for hours, and gradually let your eyes adjust to become hypersensitive to the absence of light, and then had someone take a flash photo in front of your face... so for a (possibly bad medical analogy), it might be similar to letting your nerves get into a hyper-cold-sensitive state on oxaliplatin, then blasting them with ice. In both cases, overloading a sensor that has been adjusted to its highest gain settings.
For the specific case of oxaliplatin, compression might be a good alternative. I'm not experiencing the same level of cold sensitivity I did on Folfirinox. Mild, but nowhere close.