Is there a Next Treatment for me?

Posted by fuzzy123 @fuzzy123, Jul 17, 2023

Diagnosed July 2022 with 6 to 9 Gleason score and 37 PSA . Had external beam radiation on my prostate and a single lymph node in my pelvic area ! Been given a 50% chance to live 5 years !!! Been on Lupron injections every 6 months and Abiraterone ( Zytiga ) for 1 year with my PSA undetectable for now !! These meds can only be taken for 2 - 2 1/2 years . Is there another option after this ?? Or is this treatment basically it ??

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Why is your Gleason score 6 to 9? Could you explain that to us?

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Different samples of different spots !!!

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It seems with the passage of time, the clinical evidence is that if your PSA goes below 0.2, the OS 5 and 10 years is near 100%. Even higher percentages for those below 0.1. There is a study involving retrospective patients somewhere. Not sure if these subjects are on continuing medications, but seems a lot of people are on treatment for 10 years or more. So doctors even consider PC a chronic condition.
That is my 2 cents worth. Dont mind me. I am just another layman trying to make some sense out of all these.

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@nores717

There are many treatments available! You need to be your own advocate. Learn as much as you can about your disease and find the best team for you. Don’t be afraid to travel! Have you had Foundation One or Guardant 360 testing? The results can help you determine what make work for you. As far as treatments… my husband has had Casodex, Lupron, EBRT, Chemotherapy (Docetaxel), more Chemotherapy (Docetaxel + Carboplatin), SBRT, Zytiga, SBRT again, Xtandi, and now Pluvicto. He’s stage four Gleason 9 and has been fighting for over five years. He still works full time and is doing pretty well. After round four of Pluvicto, his PSA was undetectable. We are hoping for a durable response! There are lots of other treatments such as Keytruda, Radium-223, Provenge, Darolutamide, Erleada, and other treatments on the way whichare in clinical trials.

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He said an important thing- don't be afraid to travel!

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Usually the BSOC, (Best Standard Of Care) after initial radiation and hormone therapy is Chemotherapy. There are only 2 chemo drugs proven to delay the advancement of prostate Cancer. Docetaxel Chemo that can be a bit harsh. It worked for me for about a year. Then they go to Cabazitaxel after Docetaxel fails. Cabazitaxel only worked for me for 2-3 months. Now I am a candidate for the new Pluvicto radioactive injections. That's the last line drug known to work for awhile. None of these are a cure. They buy time.

I was diagnosed Gleason 9 in 2016 and I'm still here with bone metastasis and illiac lymph node metastasis. I also have a small infiltration to my right kidney ureter. I don't have much pain and still have pretty good energy considering everything. I was initially told I had 3 years left to live and I'm starting on my 8th year with the disease with a decent quality of life. I think doctors predictions of lifespan are uber conservative.

For me, it's a lot about lowering stress, eating better and keeping a positive attitude and outlook on life. Many people say I was in denial but for the past 7 years, I did what the doctors told me to, but continued on working and not thinking much about having Cancer or dying from it. I just kept on living ALMOST as if nothing was wrong. When the Cabazitaxel failed, I had the hammer drop in my mind and have been struggling with the thought of dying and having Cancer. I think I'm somewhat coming to terms with it, but it is a process. I know I don't have many years left now, but I have to make the best of what time I have left.

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Foamhand, you are an inspiration to me I am CR,G9 etc. 2 years ago my surgeon said that I have 4-5 years. I am presently post RP, and 7 months off of meds Feeling better all the time. I hope that you and I and all here have good and long run! You’re doing great and you have a great attitude!

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@foamhand

Usually the BSOC, (Best Standard Of Care) after initial radiation and hormone therapy is Chemotherapy. There are only 2 chemo drugs proven to delay the advancement of prostate Cancer. Docetaxel Chemo that can be a bit harsh. It worked for me for about a year. Then they go to Cabazitaxel after Docetaxel fails. Cabazitaxel only worked for me for 2-3 months. Now I am a candidate for the new Pluvicto radioactive injections. That's the last line drug known to work for awhile. None of these are a cure. They buy time.

I was diagnosed Gleason 9 in 2016 and I'm still here with bone metastasis and illiac lymph node metastasis. I also have a small infiltration to my right kidney ureter. I don't have much pain and still have pretty good energy considering everything. I was initially told I had 3 years left to live and I'm starting on my 8th year with the disease with a decent quality of life. I think doctors predictions of lifespan are uber conservative.

For me, it's a lot about lowering stress, eating better and keeping a positive attitude and outlook on life. Many people say I was in denial but for the past 7 years, I did what the doctors told me to, but continued on working and not thinking much about having Cancer or dying from it. I just kept on living ALMOST as if nothing was wrong. When the Cabazitaxel failed, I had the hammer drop in my mind and have been struggling with the thought of dying and having Cancer. I think I'm somewhat coming to terms with it, but it is a process. I know I don't have many years left now, but I have to make the best of what time I have left.

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Great comment with lots of relevant info.

Thanks so much from every future reader of your comment and there will be many.

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@foamhand

Usually the BSOC, (Best Standard Of Care) after initial radiation and hormone therapy is Chemotherapy. There are only 2 chemo drugs proven to delay the advancement of prostate Cancer. Docetaxel Chemo that can be a bit harsh. It worked for me for about a year. Then they go to Cabazitaxel after Docetaxel fails. Cabazitaxel only worked for me for 2-3 months. Now I am a candidate for the new Pluvicto radioactive injections. That's the last line drug known to work for awhile. None of these are a cure. They buy time.

I was diagnosed Gleason 9 in 2016 and I'm still here with bone metastasis and illiac lymph node metastasis. I also have a small infiltration to my right kidney ureter. I don't have much pain and still have pretty good energy considering everything. I was initially told I had 3 years left to live and I'm starting on my 8th year with the disease with a decent quality of life. I think doctors predictions of lifespan are uber conservative.

For me, it's a lot about lowering stress, eating better and keeping a positive attitude and outlook on life. Many people say I was in denial but for the past 7 years, I did what the doctors told me to, but continued on working and not thinking much about having Cancer or dying from it. I just kept on living ALMOST as if nothing was wrong. When the Cabazitaxel failed, I had the hammer drop in my mind and have been struggling with the thought of dying and having Cancer. I think I'm somewhat coming to terms with it, but it is a process. I know I don't have many years left now, but I have to make the best of what time I have left.

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What an honor to read your post, I hope to be like u! Sometimes think if I’m wrong by not thinking I have cancer and keep living as it doesn’t exist!

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@foamhand

Usually the BSOC, (Best Standard Of Care) after initial radiation and hormone therapy is Chemotherapy. There are only 2 chemo drugs proven to delay the advancement of prostate Cancer. Docetaxel Chemo that can be a bit harsh. It worked for me for about a year. Then they go to Cabazitaxel after Docetaxel fails. Cabazitaxel only worked for me for 2-3 months. Now I am a candidate for the new Pluvicto radioactive injections. That's the last line drug known to work for awhile. None of these are a cure. They buy time.

I was diagnosed Gleason 9 in 2016 and I'm still here with bone metastasis and illiac lymph node metastasis. I also have a small infiltration to my right kidney ureter. I don't have much pain and still have pretty good energy considering everything. I was initially told I had 3 years left to live and I'm starting on my 8th year with the disease with a decent quality of life. I think doctors predictions of lifespan are uber conservative.

For me, it's a lot about lowering stress, eating better and keeping a positive attitude and outlook on life. Many people say I was in denial but for the past 7 years, I did what the doctors told me to, but continued on working and not thinking much about having Cancer or dying from it. I just kept on living ALMOST as if nothing was wrong. When the Cabazitaxel failed, I had the hammer drop in my mind and have been struggling with the thought of dying and having Cancer. I think I'm somewhat coming to terms with it, but it is a process. I know I don't have many years left now, but I have to make the best of what time I have left.

Jump to this post

Went back on Zolodex Then 2ys later radiated my L 1 lumbar then another year in L 2 so put me on Xtandi and Xgeva as eill as Zolodex No talk of chemo

2017 was first radiation 40 x

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