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Zonisamide kidney/ weight gain?

Epilepsy & Seizures | Last Active: Aug 12, 2023 | Replies (9)

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@lsittll

Hello @minajo
I take Zonegram with Depakote and Lamictal. I have not noticed any adverse side effects of it. Depakote lowers the metabolism and can result in weight gain itself. I have taken it for many years and have noticed the side effect. Zonisamide was added two years ago and no weight gain has been noticed. I know there is a minor possibility of the side effect of kidney damage with Zonegram but I have not seen and I hope I will never do so.

Laurie @lsittl

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Replies to "Hello @minajo I take Zonegram with Depakote and Lamictal. I have not noticed any adverse side..."

We did Depakote 15 years ago when epilepsy first diagnosed, ended up in wheelchair, couldn't walk, ammonia high in brain.. tried several since, settled on Dilantin but could keep level steady, had seizures, so tried Zonegran last August but kidney values off, 20# weight gain.. but being nonverbal autistic helps with behavior.. also had slight T3 drop but dr thinks okay as TSH is fine, on med for years..
Also hormones, menopause has to be considered ! Yikes, im a senior mom trying to help this 47 yr old daughter.. maybe drop 300 mg Zonegran to 250? Thanks

Why do you take all those seizure meds? Lamictal is really bad! Someone is totally overmedicating you, unless of course you seize constantly that's alotta dope