I have been on many different medications for anxiety and depression. My husband of 39 years was cheating on me and stealing my money. We filed for bankruptcy and the bank foreclosed on our house. We divorced. I am a nurse so very stressful job requiring a job change. I have been seeing a Psychologist for 14 years who helped me through these major issues. I’m presently well maintained on Wellbutrin 200 mg SR and Clonazepam 1 mg 3 times a day. Recently add Lexapro 10 mg. I had TMS or Transcranial magnetic stimulation. It is a huge commitment for the first 6 weeks. It is not pain free but is tolerable. I had severe headaches after every treatment. I finished in September and I feel like a new person! I have so much more energy and motivation, I can carry on a conversation, I don’t have that constant low level anxiety anymore. I am happy, look forward to things and feel more hopeful about the future. There are a couple of methods, I used Brainsway. I was on Seroquol for anxiety and sleep. Worked well but kept falling down. After major Neuro workup had to wean off Seroquel. Stopped falling! I found that tonic water helped restless legs due to Quinine. I take Somnapure for sleep which is an herbal preparation. Work well for me. Good luck. I would encourage anyone with anxiety and depression to look into TMS!