I also am very sensitive to all medications, I can't drink or take pain killers . everything makes me nauseated etc. I have only had one antipressent in my life when I was depressed because of breast cancer and I only took one pill and had such a severe side effect that I swore I would never take another. That was 12 years ago so like you I was skeptical about trying the Nortriptyline. I started with 10 mgs and slowly worked up to the 25mgs. In the beginning I was a little woosy in the mornings and was worried about feeling sedated. My body did ajust and now I might be a little slower for the first 30 minutes in the morning but I have my coffee and get on with my day without side effects. It has sure been worth it to me.