My nausea was horrible. I currently wear a scopolamine base 1 mg patch behind my ear 24x7. I change it every 3 days. I also take LORazepam as needed. I rarely use lorazepam now but they helped me get through some tough times. I am currently am on my 12th cycle. Once done, the doctor wants me to stop taking temozolomide and only take capecitabine. Since my side effects mostly come from the temozolomide, I am all too happy to stop it.