I found Creon did not increase my chronic constipation. Even though I had gas and oily stools, I still needed to take Miralax. Over 6 months, the dose of Creon was increased until I finally got to a dose that controlled it, 36,000 units two with a meal. I was starting to regain weight before the Whipple's. I was down 7 lb after surgery. I struggled with gas, abdominal discomfort and increased constipation after surgery. I am now 6 weeks out from my Whipple's. It has been difficult. To eat six times a day, I need to eat about every 3 hours. I am not hungry but I am able to eat. If I wait until I am hungry, I am not able to eat enough at a meal to get my calories in. I have been working with the hepatobiliary dietician at MSKCC and nut butters were suggested as a way to increase calories. I have tried almond and cashew butter since I was really tired of peanut butter. I have started gaining some weight. It has been a difficult six weeks. Just in the past few days I have felt more like myself fand begining to feel more hopeful about getting back to my usual state of energy