Indeed new drugs comes into play, and seems at an accelerating rate. The newer the literature or video, the harder it seems to distinguish between cure and remission. At one time, a cure is defined as surgical removal. But as good doctor points out, it may take 10- 20 years to know how good the treatment is compared to surgery. For that matter, whether surgery is 100% certain to prevent any relapse. With more clinical experience, the distinction seems less well defined.