Hi MaryJane!
The first few months were rough for me on the Big 3.
I lost a lot of weight initially but holding steady @ 105 now( 13 months on treatment). I found that taking meds at night helped with nausea and other side effects. I also started morning fruit smoothies which helped with weight gain. I also take probiotics every morning which helps!
The 6 month sputum culture is standard. If you obtain culture conversion -(No NTM detectable) at that juncture, the clock starts and you are one year from that point. I attained in November of last year.
I hope this helps!
Dee