So....following all active treatment (for which I used a local hospital), the time came for the "maintenance" part. My oncologist at the time (and mind you, I was 69) suggested Tamoxifen for 5 years. Pretty cookie cutter, no? That's the first time I sought a second opinion. I mean, I was way past menopause at that point. I went to an uptown cancer center and sure enough they prescribed a more nuanced appoach: finish the two years Tamoxifen, then 7-8 years of Anastrozole (which thankfully I tolerate with no problems). Zometa (bone protecting drug, not for everyone, and serious side effects which I thought were worth chancing because in some reliable studies Zometa has been shown to aid in preventing bone metastases) for 3 years, every 6 months by infusion. I would have no problem with continuing the AI when the time comes, but like I always say: every day we're still around gives them one more day to come up with something better. Some of these things you just have to try and see if they agree with you. In my mind the maintenance part of our treatment is just as important or maybe moreso than the critcal portion of our treatment. The cancer center I consult with currently says that a total of 10 years is the plan. Like you say, a lot can change for offerings by that time. I'm now 73.