I second what Emo said. And very well put it was, too. As a LDN user with multiple autoimmune conditions I have found that it does help with some types of pain, it helps normalize sleep, helps intestinal inflamation and helps the immune system get back in rhythm with itself. All very helpful. But I wouldn't expect it to take th place of specific drugs that are given for specific conditions. The only time I have had it take the place of a drup was I was taking Budesinide ( a steroid given by mouth for the small intestine) and the LDN healed it so thoroughly that I didn't neet it any more. And the pain it helped was caused by Sjogren's and was intractable to NSAIDs. I certainly didn't want to try anything stronger. But the LDN made it go away in less than 2 days. So it isn't for every one but it has certainly helped me.